Anitschkow cell

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Anitschkow cell
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Anitschkow myocyte in a patient with Rheumatic Heart Disease.
Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


In pathology, Anitschkow (or Anichkov[1]) cells are cells associated with, and pathognomonic for, rheumatic heart disease.[2]

They are also called caterpillar cells, as these cells have a large amount of clear cytoplasm surrounding a rod-shaped nucleus that to some resembles a caterpillar.[2] Anitschkow cells are enlarged macrophages found within granulomas (called Aschoff bodies) associated with the disease.[2]

Larger Anitschkow cells may coalesce to form multinucleated Aschoff giant cells.[2]

Etymology

Anitschkow cells were named after the Russian pathologist Nikolai Nikolajewitsch Anitschkow.[3]

References

  1. Rheumatic fever at eMedicine
  2. 2.0 2.1 2.2 2.3 Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease. St. Louis, MO: Elsevier Saunders. ISBN 0-7216-0187-1.
  3. Anitschkow's cell at Who Named It




Cardiology


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