Alginate synthase

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In enzymology, an alginate synthase (EC is an enzyme that catalyzes the chemical reaction

GDP-D-mannuronate + (alginate)n GDP + (alginate)n+1

Thus, the two substrates of this enzyme are GDP-D-mannuronate and (alginate)n, whereas its two products are GDP and (alginate)n+1.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-D-mannuronate:alginate D-mannuronyltransferase. This enzyme is also called mannuronosyl transferase. This enzyme participates in fructose and mannose metabolism.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
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  • Google Scholar references for
  • Lin TY, Hassid WZ (1966). "Pathway of algnic acid synthesis in the marine brown alga, Fucus gardneri Silva". J. Biol. Chem. 241: 5284&ndash, 97. PMID 5954796.

External links

The CAS registry number for this enzyme class is 37257-31-1.

Gene Ontology (GO) codes