Acute phase protein

(Redirected from Acute-phase reaction)
Jump to: navigation, search
Inflammatory cells and red blood cells

WikiDoc Resources for

Acute phase protein

Articles

Most recent articles on Acute phase protein

Most cited articles on Acute phase protein

Review articles on Acute phase protein

Articles on Acute phase protein in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Acute phase protein

Images of Acute phase protein

Photos of Acute phase protein

Podcasts & MP3s on Acute phase protein

Videos on Acute phase protein

Evidence Based Medicine

Cochrane Collaboration on Acute phase protein

Bandolier on Acute phase protein

TRIP on Acute phase protein

Clinical Trials

Ongoing Trials on Acute phase protein at Clinical Trials.gov

Trial results on Acute phase protein

Clinical Trials on Acute phase protein at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Acute phase protein

NICE Guidance on Acute phase protein

NHS PRODIGY Guidance

FDA on Acute phase protein

CDC on Acute phase protein

Books

Books on Acute phase protein

News

Acute phase protein in the news

Be alerted to news on Acute phase protein

News trends on Acute phase protein

Commentary

Blogs on Acute phase protein

Definitions

Definitions of Acute phase protein

Patient Resources / Community

Patient resources on Acute phase protein

Discussion groups on Acute phase protein

Patient Handouts on Acute phase protein

Directions to Hospitals Treating Acute phase protein

Risk calculators and risk factors for Acute phase protein

Healthcare Provider Resources

Symptoms of Acute phase protein

Causes & Risk Factors for Acute phase protein

Diagnostic studies for Acute phase protein

Treatment of Acute phase protein

Continuing Medical Education (CME)

CME Programs on Acute phase protein

International

Acute phase protein en Espanol

Acute phase protein en Francais

Business

Acute phase protein in the Marketplace

Patents on Acute phase protein

Experimental / Informatics

List of terms related to Acute phase protein

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

Acute-phase proteins are a class of proteins whose plasma concentrations increase (positive acute phase proteins) or decrease (negative acute phase proteins) in response to inflammation. This response is called the acute-phase reaction (also called acute phase response).

In response to injury, local inflammatory cells (neutrophil granulocytes and macrophages) secrete a number of cytokines into the bloodstream, most notable of which are the interleukins IL-1, IL-6 and IL-8, and TNF-α.

The liver responds by producing a large number of acute-phase reactants.

Examples

The notable are:

Serum albumin concentrations fall in acute disease states. For this reason albumin is sometimes referred to as a negative acute phase protein.

Clinical significance

Measurement of acute phase proteins is a useful marker of inflammation in both medical and veterinary clinical pathology. It correlates with the erythrocyte sedimentation rate (ESR).

External links

de:Akute-Phase-Proteinnl:Acutefase-eiwitsl:Beljakovina akutne faze

sv:Akutfasprotein



Linked-in.jpg