Acromegaly causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Common causes of acromegaly include pituitary adenoma and acidophil stem cell adenomas. Less common causes of acromegaly include GHRH secreting tumors as hypothalamic tumors, small cell lung cancer, adrenal adenoma, and pheochromocytoma. Other causes include GH secreting tumors as lymphoma and pancreatic islet cell tumor.

Causes

Common Causes

Acromegaly may be caused by:

Less Common Causes

Less common causes of acromegaly include:[1]

Genetic Causes

References

  1. 1.0 1.1 Melmed S, Braunstein GD, Horvath E, Ezrin C, Kovacs K (1983). "Pathophysiology of acromegaly.". Endocr Rev. 4 (3): 271–90. PMID 6354702. doi:10.1210/edrv-4-3-271. 
  2. Landis CA, Masters SB, Spada A, Pace AM, Bourne HR, Vallar L (1989). "GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours.". Nature. 340 (6236): 692–6. PMID 2549426. doi:10.1038/340692a0. 

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