Acenocoumarol

Jump to navigation Jump to search
Acenocoumarol
Clinical data
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • UK: POM (Prescription only)
Pharmacokinetic data
MetabolismHepatic
Elimination half-life8 to 11 hours
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC19H15NO6
Molar mass353.326 g/mol

WikiDoc Resources for Acenocoumarol

Articles

Most recent articles on Acenocoumarol

Most cited articles on Acenocoumarol

Review articles on Acenocoumarol

Articles on Acenocoumarol in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Acenocoumarol

Images of Acenocoumarol

Photos of Acenocoumarol

Podcasts & MP3s on Acenocoumarol

Videos on Acenocoumarol

Evidence Based Medicine

Cochrane Collaboration on Acenocoumarol

Bandolier on Acenocoumarol

TRIP on Acenocoumarol

Clinical Trials

Ongoing Trials on Acenocoumarol at Clinical Trials.gov

Trial results on Acenocoumarol

Clinical Trials on Acenocoumarol at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Acenocoumarol

NICE Guidance on Acenocoumarol

NHS PRODIGY Guidance

FDA on Acenocoumarol

CDC on Acenocoumarol

Books

Books on Acenocoumarol

News

Acenocoumarol in the news

Be alerted to news on Acenocoumarol

News trends on Acenocoumarol

Commentary

Blogs on Acenocoumarol

Definitions

Definitions of Acenocoumarol

Patient Resources / Community

Patient resources on Acenocoumarol

Discussion groups on Acenocoumarol

Patient Handouts on Acenocoumarol

Directions to Hospitals Treating Acenocoumarol

Risk calculators and risk factors for Acenocoumarol

Healthcare Provider Resources

Symptoms of Acenocoumarol

Causes & Risk Factors for Acenocoumarol

Diagnostic studies for Acenocoumarol

Treatment of Acenocoumarol

Continuing Medical Education (CME)

CME Programs on Acenocoumarol

International

Acenocoumarol en Espanol

Acenocoumarol en Francais

Business

Acenocoumarol in the Marketplace

Patents on Acenocoumarol

Experimental / Informatics

List of terms related to Acenocoumarol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Acenocoumarol is an anticoagulant that functions as a vitamin K antagonist (like warfarin). It is a derivative of coumarin and is marketed under the brand names Sintrom and Sinthrome.

Dosage

Research in the RECAVA network has discovered that two acquired factors (age and body mass index) and three genetic polymorphisms (genes VKORC1, CYP2C9 and CYP4F2) are useful to establish the correct dosage. Acenocoumarol is contraindicated during pregnancy.

External links

  • Template:DiseasesDB
  • Cesar J, García-Avello A, Navarro J, Herraez M (2004). "Aging and oral anticoagulant therapy using acenocoumarol". Blood Coagul Fibrinolysis. 15 (8): 673&ndash, 6. doi:10.1097/00001721-200412000-00007. PMID 15613922.
  • Lengyel M; SPORTIF-III Altanulmány Vizsgálói (2004). "Warfarin or acenocoumarol is better in the anticoagulant treatment of chronic atrial fibrillation?". Orv Hetil. 145 (52): 2619&ndash, 21. PMID 15724697.
  • Ufer M (2005). "Comparative pharmacokinetics of vitamin Kd antagonists: warfarin, phenprocoumon and acenocoumarol". Clin Pharmacokinet. 44 (12): 1227&ndash, 46. doi:10.2165/00003088-200544120-00003. PMID 16372822.
  • Montes R, Ruiz de Gaona E, Martínez-González M, Alberca I, Hermida J (2006). "The c.-1639G > A polymorphism of the VKORC1 gene is a major determinant of the response to acenocoumarol in anticoagulated patients". Br J Haematol. 133 (2): 183&ndash, 7. doi:10.1111/j.1365-2141.2006.06007.x. PMID 16611310.

References