ATRN

Attractin
Identifiers
Symbols	ATRN ; DPPT-L; KIAA0548; MGC126754; MGCA
External IDs	Template:OMIM5 Template:MGI HomoloGene: 22542
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Attractin, also known as ATRN, is a human gene.

Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other isoform is a secreted protein involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines.

Further reading

• Mori M, Sakurai M, Araie M (1993). "[Topical timolol and blood-aqueous barrier permeability to protein in human eyes]". Nippon Ganka Gakkai Zasshi. 96 (11): 1418–22. PMID 1476071.CS1 maint: Multiple names: authors list (link)
• Duke-Cohan JS, Morimoto C, Rocker JA, Schlossman SF (1996). "Serum high molecular weight dipeptidyl peptidase IV (CD26) is similar to a novel antigen DPPT-L released from activated T cells". J. Immunol. 156 (5): 1714–21. PMID 8596018.CS1 maint: Multiple names: authors list (link)
• Nagase T, Ishikawa K, Miyajima N; et al. (1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (1): 31–9. PMID 9628581.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Duke-Cohan JS, Gu J, McLaughlin DF; et al. (1998). "Attractin (DPPT-L), a member of the CUB family of cell adhesion and guidance proteins, is secreted by activated human T lymphocytes and modulates immune cell interactions". Proc. Natl. Acad. Sci. U.S.A. 95 (19): 11336–41. PMID 9736737.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nagle DL, McGrail SH, Vitale J; et al. (1999). "The mahogany protein is a receptor involved in suppression of obesity". Nature. 398 (6723): 148–52. doi:10.1038/18210. PMID 10086355.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gunn TM, Miller KA, He L; et al. (1999). "The mouse mahogany locus encodes a transmembrane form of human attractin". Nature. 398 (6723): 152–6. doi:10.1038/18217. PMID 10086356.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tang W, Gunn TM, McLaughlin DF; et al. (2000). "Secreted and membrane attractin result from alternative splicing of the human ATRN gene". Proc. Natl. Acad. Sci. U.S.A. 97 (11): 6025–30. doi:10.1073/pnas.110139897. PMID 10811918.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Deloukas P, Matthews LH, Ashurst J; et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gevaert K, Goethals M, Martens L; et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Friedrich D, Kühn-Wache K, Hoffmann T, Demuth HU (2003). "Isolation and characterization of attractin-2". Adv. Exp. Med. Biol. 524: 109–13. PMID 12675230.CS1 maint: Multiple names: authors list (link)
• Bunkenborg J, Pilch BJ, Podtelejnikov AV, Wiśniewski JR (2004). "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry". Proteomics. 4 (2): 454–65. doi:10.1002/pmic.200300556. PMID 14760718.CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liu T, Qian WJ, Gritsenko MA; et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMID 16335952.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wrenger S, Faust J, Friedrich D; et al. (2007). "Attractin, a dipeptidyl peptidase IV/CD26-like enzyme, is expressed on human peripheral blood monocytes and potentially influences monocyte function". J. Leukoc. Biol. 80 (3): 621–9. doi:10.1189/jlb.1105678. PMID 16835316.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)