ARPC3

Jump to navigation Jump to search
VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human
ARP2/3 complex ARPC3 (21 kDa) subunit
File:PDB 1u2v EBI.jpg
crystal structure of arp2/3 complex with bound adp and calcium
Identifiers
SymbolP21-Arc
PfamPF04062
InterProIPR007204

Actin-related protein 2/3 complex subunit 3 is a protein that in humans is encoded by the ARPC3 gene.[1][2][3]

This gene encodes one of seven subunits of the Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p21 subunit, has yet to be determined.[3]

References

  1. Welch MD, DePace AH, Verma S, Iwamatsu A, Mitchison TJ (Aug 1997). "The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly". J Cell Biol. 138 (2): 375–84. doi:10.1083/jcb.138.2.375. PMC 2138188. PMID 9230079.
  2. Machesky LM, Reeves E, Wientjes F, Mattheyse FJ, Grogan A, Totty NF, Burlingame AL, Hsuan JJ, Segal AW (Jan 1998). "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins". Biochem J. 328 (1): 105–12. PMC 1218893. PMID 9359840.
  3. 3.0 3.1 "Entrez Gene: ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa".

Further reading

External links