AA amyloidosis

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AA amyloidosis
ICD-10 E85.
ICD-9 277.3
DiseasesDB 16
eMedicine med/3388 

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AA amyloidosis


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AA amyloidosis is a form of amyloidosis associated with serum amyloid A protein (SAA), an acute-phase protein. [1]


The common feature to conditions associated with reactive systemic amyloidosis is long-standing cell breakdown due to chronic inflammatory or disease processes.

Associated conditions

It is associated with chronic inflammatory conditions, including: rheumatoid arthritis, ankylosing spondylitis, Crohn disease, ulcerative colitis, tuberculosis, bronchiectasis, chronic osteomyelitis.

Other conditions include Hodgkin disease, renal cell carcinoma.

It can be associated with nephrotic syndrome.[2]


  1. Lachmann HJ, Goodman HJ, Gilbertson JA, et al (June 2007). "Natural history and outcome in systemic AA amyloidosis". N. Engl. J. Med. 356 (23): 2361–71. doi:10.1056/NEJMoa070265. PMID 17554117.
  2. BU.

Amyloidosis Microchapters


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