5'-3' exoribonuclease 1

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5'-3' exoribonuclease 1
Identifiers
SymbolXRN1
Entrez54464
HUGO30654
OMIM607994
RefSeqNM_019001
UniProtQ8IZH2
Other data
LocusChr. 3 q23

5'-3' exoribonuclease 1 (XRN1) is an exoribonuclease enzyme encoded in humans by the XRN1 gene. This enzyme hydrolyses RNA in the 5’ to 3’ direction.[1]

References

  1. Mullen, T. E.; Marzluff, W. F. (1 January 2008). "Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'". Genes & Development. 22 (1): 50–65. doi:10.1101/gad.1622708. PMC 2151014. PMID 18172165.

External links