2,4,6-Trichlorophenol

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Overview

2,4,6-Trichlorophenol, also known as TCP, phenaclor, Dowicide 2S, Dowcide 2S, omal, is a chlorinated phenol that has been used as a fungicide, herbicide, insecticide, antiseptic,[1] defoliant, and glue preservative.[2] It is a yellow solid with a strong, sweet odour. It decomposes on heating to produce toxic and corrosive fumes including hydrogen chloride and chlorine.

Health effects

2,4,6-Trichlorophenol is carcinogenic in animals, causing lymphomas, leukemia, and liver cancer via oral exposure.[3][4] It is classified as Group B2 (probable human carcinogen) by the United States Environmental Protection Agency.[4] The technical grade of this substance may contain polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and other contaminants.[5]

Environmental effects

2,4,6-Trichlorophenol is an environmental pollutant that has been found in fresh water lakes such as the Great Lakes.[6]

See also

References

  1. Ogunniyi TAB, Oni PO, Juba A, Asaolu SO, and Kolawole DO (2000-01-05). "Disinfectants/antiseptics in the management of guinea worm ulcers in the rural areas". Acta Tropica. 74 (1): 33–38(6). doi:10.1016/S0001-706X(99)00057-1.
  2. "Safety data for 2,4,6-trichlorophenol". University of Oxford. 2005-09-05. Archived from the original on 14 October 2007. Retrieved 2007-11-16.
  3. "2,4,6-Trichlorophenol". The Carcinogenic Potency Database Project, University of Berkeley. 2007-10-03. Archived from the original on 4 December 2007. Retrieved 2007-11-16.
  4. 4.0 4.1 "2,4,6 Trichlorophenol". United States Environmental Protection Agency. 2000. Retrieved 2007-11-16. Unknown parameter |month= ignored (help)
  5. "2,4,6-Trichlorophenol". ICSC 1122. IPCS. 1998. Retrieved 2007-11-16. Unknown parameter |month= ignored (help)
  6. TP Halappa Gowdal, John D Lock, and Ruth G Kurtz (1985). "A comprehensive study of risk assessment for a hazardous compound of public health concern". Water Air and Soil Pollution. 24 (2). doi:10.1007/BF00285444. Retrieved 2007-11-16. Unknown parameter |month= ignored (help)

External links

de:2,4,6-Trichlorphenol fa:۲،۴،۶-تری‌کلروفنول uk:2,4,6-Трихлорфенол