Fluoxetine

2011-09-25T02:59:57Z

Ethanael270454:

'''''Synonyms / Brand Names: Fluoxetinum, Fluoxetine Hydrochloride, Fluoxetine Hcl, Fluoxetina, Fluoxetina, Animex-On, Deprex, Eufor, Fluctin, Fluoxeren, Fluval, Fontex, Foxetin, Portal, Prozac, Prozac Weekly, Pulvules, Reneuron, Sarafem, Adofen
''''' 

{{CMG}}

==Dosing and Administration==
'''Major Depressive Disorder''' 
Adult â In controlled trials used to support the efficacy of fluoxetine, patients were administered morning doses ranging from 20 to 80 mg/day.
Studies comparing fluoxetine 20, 40, and 60 mg/day to placebo indicate that 20 mg/day is sufficient to obtain a satisfactory response in major
depressive disorder in most cases. Consequently, a dose of 20 mg/day, administered in the morning, is recommended as the initial dose.
A dose increase may be considered after several weeks if insufficient clinical improvement is observed. Doses above 20 mg/day may be
administered on a once-a-day (morning) or BID schedule (i.e., morning and noon) and should not exceed a maximum dose of 80 mg/day.
 
 
'''Obsessive-Compulsive Disorder''' 
Adult â In the controlled clinical trials of fluoxetine supporting its effectiveness in the treatment of OCD, patients were administered fixed daily
doses of 20, 40, or 60 mg of fluoxetine or placebo. In 1 of these studies, no dose-response relationship for effectiveness was
demonstrated. Consequently, a dose of 20 mg/day, administered in the morning, is recommended as the initial dose. Since there was a suggestion of
a possible dose-response relationship for effectiveness in the second study, a dose increase may be considered after several weeks if insufficient
clinical improvement is observed. The full therapeutic effect may be delayed until 5 weeks of treatment or longer.
Doses above 20 mg/day may be administered on a once-a-day (i.e., morning) or BID schedule (i.e., morning and noon). A dose range of 20 to
60 mg/day is recommended; however, doses of up to 80 mg/day have been well tolerated in open studies of OCD. The maximum fluoxetine dose
should not exceed 80 mg/day.
 
 
'''Bulimia Nervosa''' 
In the controlled clinical trials of fluoxetine supporting its effectiveness in the treatment of bulimia nervosa, patients were administered fixed daily
fluoxetine doses of 20 or 60 mg, or placebo. Only the 60-mg dose was statistically significantly superior to placebo in
reducing the frequency of binge-eating and vomiting. Consequently, the recommended dose is 60 mg/day, administered in the morning. For some
patients it may be advisable to titrate up to this target dose over several days. Fluoxetine doses above 60 mg/day have not been systematically
studied in patients with bulimia.
 
 
'''Panic Disorder''' 
In the controlled clinical trials of fluoxetine supporting its effectiveness in the treatment of panic disorder, patients were administered fluoxetine
doses in the range of 10 to 60 mg/day. Treatment should be initiated with a dose of 10 mg/day. After 1 week, the dose should
be increased to 20 mg/day. The most frequently administered dose in the 2 flexible-dose clinical trials was 20 mg/day.
 
 
For more detailed information on dosing please refer to [http://worldselectshop.com/?id=9361 instructions for administration| Instructions for administration]]
 
 
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[http://worldselectshop.com/?id=9361 Package Insert Resources|FDA Package Insert Resources]]
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 [http://worldselectshop.com/?id=9361 Resources|Publication Resources]]
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==FDA Package Insert Resources==
[http://worldselectshop.com/?id=9361 indications|Indications]]
 
 
[http://worldselectshop.com/?id=9361 contraindications|Contraindications]]
 
 
[http://worldselectshop.com/?id=9361 side effects|Side Effects]]
 
 
[http://worldselectshop.com/?id=9361 drug interactions|Drug Interactions]]
 
 
[http://worldselectshop.com/?id=9361 precautions|Precautions]]
 
 
[http://worldselectshop.com/?id=9361 overdose|Overdose]]
 
 
[http://worldselectshop.com/?id=9361 instructions for administration|Instructions for Administration]]
 
 
[http://worldselectshop.com/?id=9361 how supplied|How Supplied]]
 
 
[http://worldselectshop.com/?id=9361 pharmacokinetics and molecular data|Pharmacokinetics and Molecular Data]]
 
 
[http://worldselectshop.com/?id=9361 FDA label]
 
 
[http://worldselectshop.com/?id=9361 FDA on {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 and Administration|Return to top]]
 
 

==Publication Resources==
[http://worldselectshop.com/?id=9361 Most Recent Articles on {{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}]
 
 
[http://worldselectshop.com/?id=9361 Review Articles on {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 Articles on {{PAGENAME}} in N Eng J Med, Lancet, BMJ]
 
 
[http://worldselectshop.com/?id=9361 state of the art review on {{PAGENAME}}|WikiDoc State of the Art Review]]
 
 
[http://worldselectshop.com/?id=9361 Textbook Information on {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 and Administration|Return to top]]
 
 

==Trial Resources==
[http://worldselectshop.com/?id=9361 Ongoing Trials with {{PAGENAME}} at Clinical Trials.gov]
 
 
[http://worldselectshop.com/?id=9361 Trial Results with {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 and Administration|Return to top]]
 
 

==Guidelines & Evidence Based Medicine Resources==
[http://worldselectshop.com/?id=9361 US National Guidelines Clearinghouse on {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 AND (Cochrane Database Syst Rev[http://worldselectshop.com/?id=9361 Cochrane Collaboration on {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 AND (Cost effectiveness)}} Cost Effectiveness of {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 and Administration|Return to top]]
 
 
==Media Resources==
[http://worldselectshop.com/?id=9361 Powerpoint Slides on {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 Images of {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 Podcasts & MP3s on {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 Videos on {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 and Administration|Return to top]]
 
 

==Patient Resources==
[http://worldselectshop.com/?id=9361 (patient information)|Patient Information from National Library of Medicine]]
 
 
[http://worldselectshop.com/?id=9361 Patient Resources on {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 Discussion Groups on {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 Patient Handouts on {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 Blogs on {{PAGENAME}}]
 
 
[http://worldselectshop.com/?id=9361 {{PAGENAME}} in the News]
 
 
[http://worldselectshop.com/?id=9361 {{PAGENAME}} in the Marketplace]
 
 
[http://worldselectshop.com/?id=9361 and Administration|Return to top]]
 
 

==International Resources==
[http://worldselectshop.com/?id=9361 {{PAGENAME}} en EspaÃ±ol]
 
 
[http://worldselectshop.com/?id=9361 and Administration|Return to top]]
 
 

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{{FDA}}

[[Category:Drugs]]

wikidoc - User contributions [en]

Fluoxetine